Georges E Grau Selected Research

Cerebral Malaria

1/2018	Differentially expressed microRNAs in experimental cerebral malaria and their involvement in endocytosis, adherens junctions, FoxO and TGF-β signalling pathways.
12/2016	Exploring experimental cerebral malaria pathogenesis through the characterisation of host-derived plasma microparticle protein content.
3/2016	A novel role for von Willebrand factor in the pathogenesis of experimental cerebral malaria.
12/2015	Mechanisms of murine cerebral malaria: Multimodal imaging of altered cerebral metabolism and protein oxidation at hemorrhage sites.
1/2014	Electron microscopic features of brain edema in rodent cerebral malaria in relation to glial fibrillary acidic protein expression.
1/2013	Endothelial cells potentiate interferon-γ production in a novel tripartite culture model of human cerebral malaria.
12/2012	FTIR imaging of brain tissue reveals crystalline creatine deposits are an ex vivo marker of localized ischemia during murine cerebral malaria: general implications for disease neurochemistry.
7/2010	Plasmodium falciparum adhesion on human brain microvascular endothelial cells involves transmigration-like cup formation and induces opening of intercellular junctions.
12/2009	Physiopathologic factors resulting in poor outcome in childhood severe malaria in Cameroon.
7/2008	Both functional LTbeta receptor and TNF receptor 2 are required for the development of experimental cerebral malaria.

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Georges E Grau Research Topics

Disease

23	Cerebral Malaria 01/2018 - 10/2002
16	Malaria 01/2018 - 10/2004
10	Infections 01/2020 - 03/2004
5	Neoplasms (Cancer) 11/2020 - 12/2007
5	Necrosis 12/2016 - 09/2003
4	Multiple Sclerosis 01/2022 - 12/2016
4	Communicable Diseases (Infectious Diseases) 01/2018 - 12/2006
3	Hemorrhage 12/2015 - 03/2004
3	Inflammation (Inflammations) 01/2011 - 01/2008
3	Anemia 12/2009 - 02/2003
2	Malignant Mesothelioma 11/2020 - 06/2020
2	Parasitic Diseases (Parasitic Disease) 01/2018 - 01/2017
2	Brain Diseases (Brain Disorder) 12/2012 - 02/2003
2	Parasitemia 05/2007 - 03/2004
2	Edema (Dropsy) 08/2005 - 03/2004
1	Brain Neoplasms (Brain Tumor) 02/2021
1	Mesothelioma 11/2020
1	Thrombosis (Thrombus) 01/2020
1	Arteriovenous Malformations (Arteriovenous Malformation) 01/2020
1	Blister (Bulla) 12/2019
1	Osteoarthritis 02/2019
1	Spontaneous Abortion (Miscarriage) 02/2017
1	Toxoplasmosis 01/2017
1	Falciparum Malaria (Plasmodium falciparum Malaria) 03/2016
1	Lung Injury 10/2015
1	Shock 10/2015
1	Cardiovascular Diseases (Cardiovascular Disease) 01/2015
1	Brain Edema (Cerebral Edema) 01/2014
1	Dehydration (Water Stress) 12/2012
1	Motor Neuron Disease (Primary Lateral Sclerosis) 12/2012
1	Ischemia 12/2012
1	Cavernous Hemangioma (Cavernous Angioma) 12/2009
1	Hemangioma (Angioma) 12/2009

Drug/Important Bio-Agent (IBA)

8	CytokinesIBA 01/2020 - 09/2003
5	Proteins (Proteins, Gene)FDA Link 12/2019 - 05/2007
5	AntigensIBA 10/2015 - 11/2006
5	Lymphotoxin-alpha (Lymphotoxin)IBA 07/2008 - 09/2003
3	Biomarkers (Surrogate Marker)IBA 06/2020 - 08/2005
3	Intercellular Adhesion Molecule-1 (Intercellular Adhesion Molecule 1)IBA 08/2012 - 02/2006
3	ChemokinesIBA 01/2011 - 12/2006
2	Fingolimod Hydrochloride (FTY720)FDA Link 12/2020 - 12/2016
2	Immunoglobulin G (IgG)IBA 05/2020 - 01/2020
2	Oxygen (Dioxygen)IBA 12/2012 - 05/2007
2	Phosphates (Orthophosphate)IBA 12/2012 - 08/2005
2	Biological ProductsIBA 01/2011 - 07/2006
2	Lactic Acid (Lactate)FDA LinkGeneric 12/2009 - 08/2005
2	LigandsIBA 03/2008 - 12/2007
2	Interferon-gamma (Interferon, gamma)IBA 04/2004 - 09/2003
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 10/2002 - 09/2002
1	B7-H1 AntigenIBA 11/2020
1	pembrolizumabIBA 11/2020
1	Dexamethasone (Maxidex)FDA LinkGeneric 11/2020
1	Formaldehyde (Formol)FDA Link 11/2020
1	ParaffinIBA 11/2020
1	Tumor Biomarkers (Tumor Markers)IBA 11/2020
1	Thrombin FDA Link 01/2020
1	Crystallins (Crystallin)IBA 01/2020
1	LipidsIBA 12/2019
1	Nucleic AcidsIBA 12/2019
1	Therapeutic UsesIBA 02/2019
1	ArtesunateIBA 01/2018
1	MicroRNAs (MicroRNA)IBA 01/2018
1	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 02/2017
1	Antimalarials (Antimalarial Agents)IBA 01/2017
1	Hydrogen Peroxide (Hydroperoxide)FDA LinkGeneric 01/2017
1	KynurenineIBA 01/2017
1	von Willebrand FactorIBA 03/2016
1	IronIBA 12/2015
1	InterleukinsIBA 10/2015
1	Sodium Channels (Sodium Channel)IBA 10/2015
1	Keratins (Keratin)IBA 10/2015
1	Aquaporins (Water Channels)IBA 10/2015
1	Interleukin-33IBA 10/2015
1	CurcuminIBA 01/2015
1	Annexin A5IBA 01/2015
1	Cycloheximide (Cicloheximide)IBA 01/2015
1	Glial Fibrillary Acidic ProteinIBA 01/2014
1	RNA (Ribonucleic Acid)IBA 08/2013
1	InterferonsIBA 01/2013
1	Phosphocreatine (Neoton)IBA 12/2012
1	CreatineIBA 12/2012
1	Vascular Cell Adhesion Molecule-1 (Vascular Cell Adhesion Molecule 1)IBA 08/2012
1	Death Domain ReceptorsIBA 01/2011
1	Epithelial Sodium ChannelsIBA 01/2011
1	Interleukin-12 (IL 12)IBA 01/2010
1	Podophyllotoxin (Condylox)FDA LinkGeneric 12/2009
1	Pharmaceutical PreparationsIBA 12/2009
1	CreatinineIBA 12/2009
1	Urea (Carbamide)FDA LinkGeneric 12/2009
1	BilirubinIBA 12/2009
1	Nitric Oxide (Nitrogen Monoxide)FDA Link 12/2009
1	Tumor Necrosis Factor Receptors (Tumor Necrosis Factor Receptor)IBA 07/2008
1	Platelet Membrane GlycoproteinsIBA 03/2008
1	ferric oxide (iron oxide)IBA 03/2008
1	Contrast MediaIBA 03/2008
1	Sulfhydryl Compounds (Thiols)IBA 01/2008
1	CystamineIBA 01/2008

Therapy/Procedure

6	Therapeutics 01/2022 - 12/2006
1	Immunotherapy 11/2020
1	Radiotherapy 01/2020